Mark Simon's journey into cancer research began in 2004, building on a foundation in plant-based nutrition, holistic health, and natural medicine that he cultivated since 1982. Driven by a firm conviction that alternatives to surgery, radiation, and chemotherapy exist through nutritional intervention and natural agents, Mark founded the Nutritional Oncology Research Institute (NORI) in 2011. Under his leadership, NORI developed the proprietary NORI Protocol — a methionine-restriction-based nutritional approach targeting universal vulnerabilities within cancer cells. Mark has guided pancreatic cancer patients and those with a wide range of diagnoses worldwide, building a program now recognized for its science-based rigor, accessibility, and compassionate continuous support. His mission remains expanding the range of nontoxic treatment choices available to every cancer patient.