Mark Simon's journey into cancer research began in 2004, building on decades of study in plant-based nutrition, holistic health, and natural medicine that started in 1982. Driven by the conviction that powerful, nontoxic nutritional alternatives exist beyond surgery, radiation, and chemotherapy, Mark founded the Nutritional Oncology Research Institute (NORI) in 2011. Under his leadership, NORI developed the NORI Protocol—a science-backed approach targeting universal vulnerabilities in cancer cells through cycled methionine restriction and proprietary nutraceuticals. His work has supported survivors of breast, prostate, thyroid, and advanced cancers worldwide, achieving estimated response rates over 90% for key cancer types. Mark continues to lead NORI's research and client support programs, making evidence-based nutritional oncology accessible and affordable to patients across the globe.